Just picked up a .22 250 and was wondering what everyone's favorite load is for the .22 250.
Been 20 or more years since I last loaded 22-250. What I can tell you from my experience loading and shooting it in two rifles. Both rifles were Remington 700's, one BDL with heavy factory varmint barrel and an ADL with standard barrel I won in a poker game.
My best shot to shot accuracy was achieved with hand loads at least 10% below published max. The three powders I got the best accuracy were IMR 4350, IMR 3031 and Winchester 748. Keep in mind with me working from memory I might be wrong about powder. Which ever powder load I derived from a 1970's manual that proved to be best. I was shooting 200 yard quarter sized clusters bench rested with the heavy barrel.
I quickly discovered max published velocity, accuracy suffers, more strays and barrel life is supposedly reduced. Loading data of years past was more generous than published today. My 1970's 10% below max might exceed today's published max.
No need to push it to max. Losing 200FPS for superior accuracy well worth it. The 22-250 below max is still pushing the bullet faster than any other center fire 22 except the barrel burning 220 Swift. You will get more than enough oomph to immediately drop a coyote or roll a bobcat. I'm guessing again but I believe it was a Hornady or Speer 53gr HP that was literally explosive on varmints.
Keep your bore very clean. The hyper velocity has a tendency to copper foul the barrel. I've read on various boards Varget powder is wonderful for 22-250. It wasn't around when I was loading 22-250 but might be worth a try.